Mass Spectrometry Sample Submission Guidelines

Mass spectrometry (MS) is a powerful analytical technique capable of providing qualitative and quantitative analytical data for analytes ranging from nanomolar to atomic molar amounts. It has been applied successfully to a very wide range of analytical problems in the chemistry, biology and environmental sciences. For example, it is used to obtain information about the molecular weight and chemical structure of peptides, proteins, carbohydrates, oligonucleotides, natural products and drug metabolites.

Correct sample submission guidelines are essential for obtaining accurate and reliable results from MS analysis. By following the correct sample submission guidelines, researchers can achieve the best possible results and make important scientific discoveries.

MS Sample Requirements

Sample Requirements for GC-MS:

In order to direct injection, the sample must be in liquid or gaseous form. In addition, headspace analysis can be used to analyze the compounds off gassed by the solid.

For liquid or gas samples, the recommended sample size is several micro liters. In the case of headspace analysis of a solid, the sample size should be between 0.5-1 gram.

Please indicate the approximate composition and relative content of the sample. Please provide the structural formula, molecular weight or functional groups of the sample components as much as possible.

Sample Requirements for LC-MS:

Flammable, explosive, toxic, and corrosive samples must be clearly labeled.

To ensure accurate and reliable analysis results, samples must be completely dissolved and free from mechanical impurities. For samples that have not been prepared as a solution, please indicate the solvent used, and for samples that have already been prepared as a solution, please specify the concentration.

Please provide the structural formula, molecular weight, or functional groups contained in the sample as much as possible, so that the ionization mode can be selected. If there are specific experimental requirements, please provide the details.

In order to prevent the damage of the ion source, the sample cannot contain metal ions, surfactants, and non-volatile salts such as phosphates and borates.

MS Analysis Turnaround Time

The analysis time for MS can vary depending on the complexity of the sample, the instrument used, and the number of samples analyzed. Simple samples may require less analysis time, while some samples may require longer analysis time due to the presence of complex matrices or low analyte concentrations.

After receiving your sample, we will dispatch the duly processed data to you within the temporal span of 2-5 working days. Nevertheless, if expeditious delivery of data is of utmost importance to you, please let us know in advance in order to make the necessary arrangements.

Overall, Alfa Chemistry is committed to providing high-quality MS analysis services to our customers worldwide. Our experienced analysts and state-of-the-art facilities allow us to provide accurate and reliable results in a timely manner. We are dedicated to meeting the unique needs of each of our clients and ensuring their success in their scientific endeavors. If you have any questions, please do not hesitate to contact us.

Our services are for research use only.